Manchester United spurned a chance to move into the Premier League's top four after striker Zlatan Ibrahimovic missed a penalty in a 1-1 draw against 10-man Bournemouth on Saturday.
A Roberto Firmino hat-trick proved the highlight of Liverpool's 5-1 demolition of Arsenal as the Premier League leaders opened a nine-point gap over Tottenham Hotspur, who lost 3-1 to Wolverhampton Wanderers.
The visitors got off to the perfect start when a mix up at the back saw Riyad Mahrez square for Jamie Vardy to tap into an open goal in front of the Kop in the third minute. Liverpool looked for an immediate riposte, but Salah missed two gilt-edged opportunities before Sadio Mane saw an effort disallowed for offside as Juergen Klopp's men grew frustrated.
Images from Premier League matches played on Wednesday.
Watford's hopes of avoiding relegation suffered a double blow on Tuesday when they were thrashed 4-0 at home by Manchester City and then slipped into the Premier League relegation zone after fellow strugglers Aston Villa beat Arsenal in the late game.
The win moved Spurs up to third but unbeaten Manchester City still looked in a class of their own at the top as Leroy Sane scored twice in a 4-0 stroll over West Ham United.
Manchester United battled back from two goals down to beat Newcastle United 3-2 at Old Trafford on Saturday as a 90th-minute winner from Alexis Sanchez completed a spirited comeback to ease the pressure on manager Jose Mourinho.
Manchester United striker Romelu Lukaku defended Jose Mourinho's confrontational style of management, saying that the Portuguese deserves respect for not hiding his true feelings like several Premier League bosses.
Watford climbed into the top four of the Premier League after Tom Cleverley's 92nd-minute goal gave them a 2-1 victory over Arsenal at Vicarage Road on Saturday.
Photos from the English Premier League matches played on Saturday
Jamie Vardy equalled the English Premier League record by scoring for a 10th successive match as his Leicester City side went top after winning 3-0 at Newcastle United while champions Chelsea ended their slump with a 1-0 win over Norwich City on Saturday.
Imperious Liverpool extended their Premier League home winning streak against Arsenal to six on Saturday with an easy 4-0 victory that lifted them to second in the table.
Chelsea made light of striker Diego Costa's absence to extend their lead at the top of the Premier League to seven points with a 3-0 win at champions Leicester City.
Manchester United manager Jose Mourinho was sent off for the second time in a month on Sunday as the controversial coach watched his side draw 1-1 at home to West Ham United and lose more ground in the English Premier League title race.
Arsenal manager Unai Emery was pleased with his team's first away clean sheet of the season.
Liverpool put their recent troubles behind them, showing touches of their best early-season vibrancy to overcame Arsenal 3-1 at a jubilant Anfield and leapfrog the Gunners into third place in the Premier League on Saturday.
IMAGES from the English Premier League matches played on Tuesday
IMAGES from Saturday's English Premier League matches.
Images from the English Premier League matches played on Saturday.
Arsenal's victory was scrappy and nervy but Laurent Koscielny's 72nd-minute winner was enough to move them two points clear at the summit after LeicesterCity's surprise push faltered with a goalless draw at home to 10-man Bournemouth.
Liverpool's dream run was demolished in the most unlikely fashion by strugglers Watford on Saturday in what must be considered the most extraordinary reverse of the entire Premier League season. On the evening when the European champions were expected to complete the best sequence in the history of English football's top-flight with a 19th straight league victory, they were instead hammered 3-0 by the team lying one from bottom. Images from the EPL matches played on Saturday.
IMAGES from the English Premier League match played on Saturday
Images from the English Premier League matches on Saturday.
Liverpool made it three wins out of three as Mohamed Salah scored twice in a convincing 3-1 victory over Arsenal on Saturday to take control at the top of the Premier League.
As the countdown to 2018 starts, it's time to rewind those moments in sport that stood out this year.
A round-up of Saturday's action in the Premier League.
Images from the EPL matches played on Sunday
Arsenal slumped to a last-gasp 2-1 Premier League defeat at relegation-threatened Brighton & Hove Albion on Saturday in a blow to the London club's chances of securing European football next season. Watford's Craig Dawson grabbed a stoppage-time equaliser with an overhead kick to earn his side a 1-1 draw with Leicester City on Saturday and a vital point in their battle for Premier League survival.
Images from the English Premier League matches played on Saturday
Images from the English Premier League matches played at Old Trafford on Saturday
IMAGES from the English Premier League matches played on Saturday.
Liverpool beat Leicester City 2-1 to post a fourth successive Premier League victory but conceded their first goal of the season after a nightmare mistake by new keeper Alisson.
News of all that's transpired on and off the football field
Sean Dyche's Burnley side looked to have secured a crucial point in their fight to move clear of the bottom three but Eriksen broke their hearts with a clinical finish for third-placed Spurs in the 91st minute.
City's Aguero doubtful starter for Watford trip
Manchester City made sure of third place in the Premier League when they romped to a 5-0 win at Watford on Sunday to ensure a Champions League berth for next season.
News of all that's transpired on and off the football field
Raheem Sterling scored a hat-trick as champions Manchester City made a convincing start to their title defence with a 5-0 win over West Ham United.
Philippe Coutinho inspired Liverpool to a comfortable 3-1 home win over Everton in the 228th Merseyside derby on Saturday to move provisionally up to third in the Premier League.
News of all that's transpired on and off the football field.